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Explore antimicrobial resistance genes from the literature

drmA

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to drmA

Browse AMR rules for drmA

Overview

Mechanism: frameshift mutation
Drug Classes: daptomycin
Organisms: Enterococcus faecalis
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
N150fs	-	frameshift mutation	Enterococcus faecalis	daptomycin	Card Database	Candidate
L4Ter	-	nonsense mutation	Enterococcus faecalis	daptomycin	Card Database	Candidate

Papers1

1

Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance.

PMID 23959318 · 2013

Enterococcus faecalis drmA with mutation conferring daptomycin resistance; CARD accession: CARD:3003813

Mutation Information

drmA: p.N150fs drmA: p.L4Ter

Protein Change: N150fs, L4Ter
Organisms: Enterococcus faecalis
Confers Resistance To: daptomycin
Effect on Function: frameshift mutation; nonsense mutation
Source Database: Card Database