drrA

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efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to drrA

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: real-time semiquantitative PCR
Drug Classes: rifampicin, isoniazid
Organisms: Mycobacterium tuberculosis
Geographic Location: Iran
Papers: 1
Databases: Reslit

Papers1

Comparison Of drrA And drrB Efflux Pump Genes Expression In Drug-Susceptible And -Resistant Mycobacterium tuberculosis Strains Isolated From Tuberculosis Patients In Iran.

PMID 31807034 · 2019

The study found that drrA and drrB efflux pump genes were significantly overexpressed in multidrug-resistant (MDR) and drug-resistant Mycobacterium tuberculosis (MTB) isolates compared to susceptible isolates, indicating their role in antibiotic resistance.

Gene Information

Gene Name: drrA
Allele: drrA
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: rifampicinisoniazid
Organisms Tested In: • Mycobacterium tuberculosis
Geographic Location: Iran
Validation Method: real-time semiquantitative PCR

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drrA

Gene Information

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drrA

Gene Information