Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
putative transcriptional regulator
Overview
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance.
The study identifies 33 known AMR genes and 24 new genetic signatures of AMR in Mycobacterium tuberculosis using machine learning and structural analysis. It also reveals 97 epistatic interactions across 10 resistance classes and provides mechanistic insights into the selection of these genes.
Comparison Of drrA And drrB Efflux Pump Genes Expression In Drug-Susceptible And -Resistant Mycobacterium tuberculosis Strains Isolated From Tuberculosis Patients In Iran.
The study found that drrA and drrB efflux pump genes were significantly overexpressed in multidrug-resistant (MDR) and drug-resistant Mycobacterium tuberculosis (MTB) isolates compared to susceptible isolates, indicating their role in antibiotic resistance.
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