dut

deoxyuridine triphosphatase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to dut

Browse AMR rules for dut

Overview

Mechanism: dUTP diphosphatase Dut
Drug Classes: trimethoprim sulfamethoxazole
Organisms: Burkholderia pseudomallei
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V77A	-	-	Burkholderia pseudomallei	trimethoprim sulfamethoxazole	Reslit	Candidate
G91A	-	dUTP diphosphatase Dut	Burkholderia pseudomallei	trimethoprim sulfamethoxazole	Reference Gene Catalog	Candidate

Papers2

1

Taking the next-gen step: Comprehensive antimicrobial resistance detection from Burkholderia pseudomallei.

PMID 33285499 · 2021

Mutation Information

Protein Change: V77A
Organisms: Burkholderia pseudomallei
Confers Resistance To: trimethoprim sulfamethoxazole
Validation Method: experimental validation
Source Database: Reslit

2

Raising the Stakes: Loss of Efflux Pump Regulation Decreases Meropenem Susceptibility in Burkholderia pseudomallei.

PMID 29394337 · 2018

dut

Mutation Information

Protein Change: G91A
Organisms: Burkholderia pseudomallei
Confers Resistance To: trimethoprim sulfamethoxazole
Effect on Function: dUTP diphosphatase Dut
Source Database: Reference Gene Catalog