elsL

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ld-carboxypeptidase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to elsL

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Validation StatusCandidate

Overview

Validation Method: genetic knockout and meropenem killing assay
Drug Classes: carbapenems
Organisms: Acinetobacter baumannii
Papers: 1
Databases: Reslit

Papers1

Peptidoglycan Recycling Promotes Outer Membrane Integrity and Carbapenem Tolerance in Acinetobacter baumannii.

PMID 35638738 · 2022

The study identifies pbpG and elsL as key contributors to meropenem tolerance in Acinetobacter baumannii through their roles in peptidoglycan recycling and maintaining outer membrane integrity.

Gene Information

Gene Name: elsL
Allele: elsL
Encodes: ld-carboxypeptidase
Source Database: Reslit
Confers Resistance To: carbapenems
Organisms Tested In: • Acinetobacter baumannii
Validation Method: genetic knockout and meropenem killing assay
Sequence Accession: GSE190441

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elsL

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elsL

Gene Information