Browse AMR Genes

Explore antimicrobial resistance genes from the literature

eptC

phosphoethanolamine transferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to eptC

Browse AMR rules for eptC

Overview

Drug Classes: polymyxin b
Organisms: Campylobacter jejuni
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
P360Q	-	-	Campylobacter jejuni	polymyxin b	Reslit	Candidate
-	C360A	-	Campylobacter jejuni	polymyxin b	Reslit	Candidate

Papers1

1

The bile salt deoxycholate induces Campylobacter jejuni genetic point mutations that promote increased antibiotic resistance and fitness.

PMID 36619995 · 2022

The mutation was identified in isolates grown in DOC-supplemented medium.

Mutation Information

eptC: p.P360Q eptC: c.C360A

Protein Change: P360Q
Nucleotide Change: C360A
Organisms: Campylobacter jejuni
Confers Resistance To: polymyxin b
Validation Method: whole genome sequencing of adapted isolates
Source Database: Reslit