erm(30)

23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(30)

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Target modification
Drug Classes: STREPTOGRAMIN, QUINUPRISTIN, PRISTINAMYCIN IA, CLINDAMYCIN, LINCOMYCIN, MACROLIDE, ERYTHROMYCIN, VIRGINIAMYCIN S, LINCOSAMIDE
Organisms: Streptomyces venezuelae
Alleles: 2
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder Database

Allele Variants2

Allele	Database	Papers	Drug Classes	Organisms	Countries	Years	Sequence Accession	Protein Accession
Erm(30)	Card DatabaseReference Gene CatalogResFinder Database	3	STREPTOGRAMIN, QUINUPRISTIN +7	Streptomyces venezuelae	-	-	AF079138.1	AAC69328.1
erm(30)	ResFinder Database	1	QUINUPRISTIN, PRISTINAMYCIN IA +4	Streptomyces venezuelae	-	1998	AF079138	-

Papers1

PMID N/A

Gene Information

Gene Name: erm(30)
Allele: Erm(30)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(30)
Source Database: Reference Gene Catalog
Mechanism: Target modification
Confers Resistance To: STREPTOGRAMINQUINUPRISTINPRISTINAMYCIN IACLINDAMYCINLINCOMYCINMACROLIDEERYTHROMYCINVIRGINIAMYCIN SLINCOSAMIDE
Organisms Tested In: • Streptomyces venezuelae
Sequence Accession: AF079138.1
Protein Accession: AAC69328.1
Notes: 23S rRNA methylase; Azithromycin, Spiramycin resistance in Staphylococcus sp. and Streptococcus sp.; If inducible phenotype, patterns of spiramycin, lincomycin and clindamycin resistance may vary

PMID N/A

Gene Information

Gene Name: erm(30)
Allele: Erm(30)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(30)
Source Database: ResFinder Database
Mechanism: Target modification
Confers Resistance To: STREPTOGRAMINQUINUPRISTINPRISTINAMYCIN IACLINDAMYCINLINCOMYCINMACROLIDEERYTHROMYCINVIRGINIAMYCIN SLINCOSAMIDE
Organisms Tested In: • Streptomyces venezuelae
Sequence Accession: AF079138.1
Protein Accession: AAC69328.1
Notes: 23S rRNA methylase; Azithromycin, Spiramycin resistance in Staphylococcus sp. and Streptococcus sp.; If inducible phenotype, patterns of spiramycin, lincomycin and clindamycin resistance may vary

PMID N/A

Gene Information

Gene Name: erm(30)
Allele: Erm(30)
Encodes: 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(30), Erm 23S ribosomal RNA methyltransferase
Source Database: Card Database
Mechanism: Target modification, antibiotic target alteration
Confers Resistance To: STREPTOGRAMINQUINUPRISTINPRISTINAMYCIN IACLINDAMYCINLINCOMYCINMACROLIDEERYTHROMYCINVIRGINIAMYCIN SLINCOSAMIDE
Organisms Tested In: • Streptomyces venezuelae
Sequence Accession: AF079138.1
Protein Accession: AAC69328.1
Notes: 23S rRNA methylase; Azithromycin, Spiramycin resistance in Staphylococcus sp. and Streptococcus sp.; If inducible phenotype, patterns of spiramycin, lincomycin and clindamycin resistance may vary, ARO:3001265

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.

PMID 9770448 · 1998

Gene Information

Gene Name: erm(30)
Allele: erm(30)
Source Database: ResFinder Database
Mechanism: Target modification
Confers Resistance To: QUINUPRISTINPRISTINAMYCIN IACLINDAMYCINLINCOMYCINERYTHROMYCINVIRGINIAMYCIN S
Organisms Tested In: • Streptomyces venezuelae
Sequence Accession: AF079138
Notes: 23S rRNA methylase; Azithromycin, Spiramycin resistance in Staphylococcus sp. and Streptococcus sp.; If inducible phenotype, patterns of spiramycin, lincomycin and clindamycin resistance may vary

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Allele

Database

Papers

Drug Classes

Organisms

Countries

Years

Sequence Accession

Protein Accession

Erm(30)

Card DatabaseReference Gene CatalogResFinder Database

STREPTOGRAMIN, QUINUPRISTIN +7

Streptomyces venezuelae

AF079138.1

AAC69328.1

erm(30)

ResFinder Database

QUINUPRISTIN, PRISTINAMYCIN IA +4

Streptomyces venezuelae

1998

AF079138

erm(30)

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