Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(49)
Overview
Antibiotic resistance in probiotic bacteria.
Antibiotic resistance in probiotic bacteria.
A Gene Homologous to rRNA Methylase Genes Confers Erythromycin and Clindamycin Resistance in Bifidobacterium breve.
The study identifies a novel gene, erm(49), which is homologous to rRNA methylase genes and confers high-level resistance to erythromycin and clindamycin in Bifidobacterium breve CECT7263. The gene was experimentally validated through cloning and MIC testing.
Genomic insights into antibiotic resistance and mobilome of lactic acid bacteria and bifidobacteria.
The study identified several acquired and intrinsic antimicrobial resistance genes in lactic acid bacteria and bifidobacteria, including tetW, ANT(6)-Ia, aac(6')-Ie-APH(2'')-Ia, erm(B), erm(49), cat, dfrG, arr-4, and fosXCC. Additionally, mutations in S12, rsmG, Lsa(A), MsrC, and PBP5 were associated with resistance to various antibiotics.
Genomic profiling of pan-drug resistant proteus mirabilis Isolates reveals antimicrobial resistance and virulence gene landscape.
The study identified multiple antimicrobial resistance genes in pan-drug resistant Proteus mirabilis isolates, including genes conferring resistance to aminoglycosides, beta-lactams, tetracyclines, sulfonamides, and others. These genes were found on the chromosome and contributed to the isolates' resistance to various antibiotic classes.
Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome.
The study investigated the metabolism of human milk oligosaccharides (HMOs) by bifidobacteria and lactobacilli isolated from human milk and mother-infant fecal samples, along with their antibiotic resistance profiles. Bifidobacterium bifidum showed the highest HMO degradation capability and was the most antibiotic-susceptible species, whereas Bifidobacterium animalis subsp. lactis was resistant to most tested antibiotics.
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