Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Erm 23S ribosomal RNA methyltransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| ErmH | Card DatabaseReslit | 3 | macrolides, lincosamides +1 | Streptomyces thermotolerans +2 | China | 2022, 2025 | M16503.1 | AAC32026.1 |
| Erm(H) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | macrolides, lincosamides +9 | environmental bacteria +2 | Europe, Global | 1987, 2011, 2023 | V00622|X53796|X07848|M11587|P20074|K00544|X02529|AY355285|NC_002013|U15027|M35190|S48276|M93113|M55620|M58472|AF047479|AJ009818|AF036933|AF462019|AF878850|M64556|M22614|AF071555|AJ549214|X59968|U09991|Z12001|U85507|AJ579365|HM537013 | AAC32026.1 |
| erm(H) | ResFinder Database | 1 | QUINUPRISTIN, PRISTINAMYCIN IA +4 | Streptomyces thermotolerans | - | 1987 | M16503 | - |
Environmental macrolide-lincosamide-streptogramin and tetracycline resistant bacteria.
The paper discusses the characterization of environmental macrolide-lincosamide-streptogramin (MLS) and tetracycline resistance genes, highlighting the diversity and distribution of these genes in environmental bacteria. It identifies several MLS resistance genes such as erm(H), erm(I), erm(N), and others, as well as tetracycline resistance genes like tetA(P), tet(V), and tet(X).
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
Cloning and nucleotide sequence of a carbomycin-resistance gene from Streptomyces thermotolerans.
Cloning and nucleotide sequence of a carbomycin-resistance gene from Streptomyces thermotolerans.
Cloning and nucleotide sequence of a carbomycin-resistance gene from Streptomyces thermotolerans.
Cloning and nucleotide sequence of a carbomycin-resistance gene from Streptomyces thermotolerans.
The resistomes of Mycobacteroides abscessus complex and their possible acquisition from horizontal gene transfer.
The study identifies numerous AMR genes in Mycobacteroides abscessus complex, highlighting the widespread presence of resistance to multiple antibiotic classes, including beta-lactams, aminoglycosides, glycopeptides, and others. Key findings include the detection of beta-lactamases like blaLAP-1 and blaTLA-2, 23S rRNA methyltransferases such as erm(33), erm(43), and erm(44), and various aminoglycoside modifying enzymes. Additionally, vancomycin resistance genes like vanA, vanB, and vanC were identified, along with efflux pump genes contributing to multidrug resistance.
Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica.
The study identified several antimicrobial resistance genes in Nocardia cyriacigeorgica, including VanSO and VanRO for vancomycin resistance, erm(O)-Irm, srmB, and ermH for macrolide resistance, bla1 and bcl for beta-lactam resistance, CTX-M and KPC for cephalosporin and carbapenem resistance, tetA(58) and tetB(58) for tetracycline resistance, folC and folP for sulfonamide resistance, rbpA and rpoB2 for rifamycin resistance, murA and AbaF for fosfomycin resistance, cmlR for chloramphenicol resistance, and VatF and VatE for streptogramin resistance.
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