Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Erm 23S ribosomal RNA methyltransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| ErmQ | Card DatabaseReslit | 4 | clindamycin, macrolides +3 | Clostridium perfringens +2 | China | 1994, 2023, 2024 | L22689.1 | AAC36915.1 |
| Erm(Q) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 10 | macrolides, lincosamides +13 | Aggregatibacter +10 | Global, Egypt, Qinghai province|Tibetan sheep, China, Europe, France | 1994, 2020, 2021, 2023, 2025 | V00622|X53796|X07848|M11587|P20074|K00544|X02529|AY355285|NC_002013|U15027|M35190|S48276|M93113|M55620|M58472|AF047479|AJ009818|AF036933|AF462019|AF878850|M64556|M22614|AF071555|AJ549214|X59968|U09991|Z12001|U85507|AJ579365|HM537013 | AAC36915.1 |
| erm[Q] | Reslit | 1 | erythromycin | Clostridium perfringens | Japan | 2025 | NSUB001450|DRA017675 | - |
| erm(Q) | ResFinder Database | 1 | QUINUPRISTIN, PRISTINAMYCIN IA +4 | Clostridium perfringens | - | 1994 | L22689 | - |
Antimicrobial Resistance in Bacteria: Mechanisms and Current Challenges
This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.
Antimicrobial Resistance in Clostridium and Brachyspira spp. and Other Anaerobes.
The paper describes the antimicrobial resistance mechanisms in Clostridium and Brachyspira spp. and other anaerobes, focusing on the genetic basis of resistance to various antibiotics, including tetracyclines, macrolides, lincosamides, chloramphenicol, and others. It highlights the role of specific genes such as tet, erm, and cat in conferring resistance.
Virulence Determinants and Antimicrobial Profiles of Pasteurella multocida Isolated from Cattle and Humans in Egypt.
The study identified multiple antimicrobial resistance genes in Pasteurella multocida isolates from cattle and humans in Egypt, including erm(Q), erm(42), mph(E), msr(E), intl1, intl2, blaCTX-M, blaCTX-M-1, and blaTEM, which confer resistance to various antibiotics such as erythromycin, azithromycin, cefotaxime, and ampicillin.
Genome characteristics of the optrA-positive Clostridium perfringens strain QHY-2 carrying a novel plasmid type.
The study identifies the optrA gene, which confers resistance to oxazolidinones and phenicols, along with other resistance genes such as fexA, erm(A), erm(B), erm(Q), aac(6')-aph(2''), and lnu(P) in the optrA-positive Clostridium perfringens strain QHY-2. These genes are located on a novel plasmid type, highlighting the potential for horizontal transmission of antibiotic resistance among C. perfringens strains.
Molecular characteristics and phylogenetic analysis of Clostridium perfringens from different regions in China, from 2013 to 2021.
The study identified various AMR genes in Clostridium perfringens isolates from China, including mprF, tetA(P), tetB(P), ErmQ, LnuP, AAC(6′)-Ie-APH(2″)-Ia, ANT(6)-Ib, tet44, and ErmB, which confer resistance to antibiotics such as penicillin, tetracycline, clindamycin, and aminoglycosides.
Antimicrobial Resistance of Clostridioides difficile in Children from a Tertiary Pediatric Hospital in Shanghai, China.
The study identifies various antimicrobial resistance genes in Clostridioides difficile isolates from children, including those conferring resistance to aminoglycosides, macrolides, fluoroquinolones, glycopeptides, lincosamides, tetracyclines, and others. Notably, the pCD-METRO plasmid and vanA/B were not detected, indicating alternative resistance mechanisms.
Size Distribution and Pathogenic Potential of Culturable Airborne Clostridium spp. in a Suburb of Toyama City, Japan.
The study identified several antimicrobial resistance genes in Clostridium perfringens isolates, including mprF, tetA[P], tetB[P], erm[Q], cfrC, and mef[A]. These genes confer resistance to defensin, tetracycline, erythromycin, linezolid, phenicol, and macrolide antibiotics.
Genome MLST scheme for tracing genetic diversity and multidrug resistance of food animal-derived Clostridium perfringens.
The study identified tetracycline resistance genes tetA(P) and tetB(P) as the most prevalent in C. perfringens isolates, along with other resistance genes such as erm(Q) and lnu(P).
Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.
The study identified several tetracycline, aminoglycoside, and MLS resistance genes in the fecal microbiome of gilts, with no significant increases in ARG abundance following exposure to semen extenders containing antibiotics.
Commensal Clostridia in the preterm gut as reservoirs of antimicrobial resistance: susceptibility profiles, and resistance genes.
The study identifies tetracycline and clindamycin resistance genes (tet and erm) in various Clostridia species from preterm infants, highlighting their role as reservoirs of antimicrobial resistance.
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.
The ermQ gene was identified as the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens, and it was shown to confer resistance to erythromycin, clindamycin, and streptogramin B when expressed in Escherichia coli.
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.
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