The study identifies erm(X) as a prevalent determinant of tylosin resistance in Arcanobacterium pyogenes, which confers resistance to macrolides, lincosamides, and streptogramin B antibiotics.

The study identified the presence of tetracycline resistance genes tet(O) and tet(W), as well as the erythromycin resistance gene erm(X), in Bifidobacterium thermophilum and Bifidobacterium pseudolongum isolates from animal sources.

The study reports the first case of a multidrug-resistant Corynebacterium diphtheriae strain in Canada, which was resistant to clindamycin, erythromycin, tetracycline, and trimethoprim-sulfamethoxazole. The resistance to erythromycin and clindamycin was associated with the ermX gene.

This paper characterizes several beta-lactamases, including TEM-1, SHV-1, CTX-M-15, and NDM-1, which confer resistance to various beta-lactam antibiotics. It also identifies erm(B) and mef(A) as mechanisms of macrolide, lincosamide, and streptogramin B resistance. Additionally, aadA1 and aac(6')-Ib are noted for aminoglycoside resistance, while catA1 and floR contribute to chloramphenicol resistance. The vanA gene is associated with glycopeptide resistance, and mcr-1 is linked to polymyxin resistance.

The study identifies the tet(W) gene on plasmid pJA144188 as a novel tetracycline resistance determinant in Corynebacterium resistens DSM 45100, which confers resistance to tetracycline, doxycycline, and minocycline when expressed in Corynebacterium glutamicum.

The study characterizes the antimicrobial resistance profile of Dermabacter hominis, identifying resistance to daptomycin, erythromycin, clindamycin, and other antibiotics. It also identifies specific genes associated with resistance, including erm(X), cmx, strAB, sul1, and a mutation in gyrA linked to fluoroquinolone resistance.

The genome of Corynebacterium imitans DSM 44264 reveals the presence of several antibiotic resistance genes, including erm(X), aphA1-IAB, strA-strB, and cmx, which are consistent with its multidrug-resistant profile.

The study identified multidrug-resistant Corynebacterium kroppenstedtii strain CNM633/14 carrying resistance genes erm(X), tet(W), cmx, aphA1-IAB, strAB, and sul1, which confer resistance to various antibiotics including erythromycin, clarithromycin, azithromycin, clindamycin, tetracycline, chloramphenicol, kanamycin, streptomycin, and cotrimoxazole.

The review discusses the impact of antimicrobial usage in beef production on the emergence and spread of antimicrobial resistance (AMR) in bovine pathogens. It highlights the role of antimicrobial use in promoting AMR, particularly in respiratory and liver abscess pathogens, and emphasizes the need for judicious use to mitigate risks to both animal and human health.

The review discusses the impact of antimicrobial usage in beef production on the emergence and spread of antimicrobial resistance (AMR) in bovine pathogens. It highlights the role of antimicrobial use in promoting AMR, particularly in respiratory and liver abscess pathogens, and emphasizes the need for judicious use to mitigate risks to both animal and human health.

The study identifies several AMR genes and mutations in Corynebacterium striatum, including bla, erm(X), erm(B), aph(3')-Ic, aac(3)-XI, aph(3'')-Ib, and aph(6)-Id, along with gyrA mutations contributing to fluoroquinolone resistance.

The study reports the draft genome of a multidrug-resistant Corynebacterium striatum isolate, identifying several resistance genes including tetA, tetB, vanW, ermX, aph(3')-Ia, strA-strB, bla, and cmx, along with a mutation in the gyrA gene contributing to quinolone resistance.

The study identifies the erm(X) and erm(C) genes as responsible for MLSB resistance in Corynebacterium spp., with erm(X) being the primary gene detected and erm(C) being reported for the first time in this context.

High levels of Bifidobacterium in early life are associated with reduced levels of antimicrobial resistance (AMR) in the gut microbiome. Specifically, the gene ermX, encoding a 23S rRNA methyltransferase, was found to be significantly enriched in high-Bifidobacterium samples and is associated with resistance to macrolides, lincosamides, and streptogramin B.

The study identifies various antibiotic resistance genes (ARGs) associated with multidrug resistance, including macrolide, beta-lactam, tetracycline, and methicillin resistance genes, highlighting the presence of these genes in postmortem microbiome samples.

The study identified multiple AMR genes (ermX, aphA, cmx) and mutations in the gyrA gene associated with fluoroquinolone resistance in multidrug-resistant Corynebacterium striatum isolates.

The study identified blaA as a β-lactamase gene responsible for ampicillin resistance, ermX as a gene responsible for erythromycin resistance, and mutations in gyrA and rpoB associated with levofloxacin and rifampicin resistance in Corynebacterium urealyticum isolates.

The study identified multiple antimicrobial resistance genes in bacterial isolates from chronic non-healing wounds, including beta-lactamases, aminoglycoside modifying enzymes, macrolide resistance genes, and others. These genes were found in various bacterial species such as E. coli, S. aureus, P. aeruginosa, and others.

The study identified ermX and tetO genes in Bifidobacterium pseudocatenulatum isolates from Vietnam, which confer resistance to azithromycin and tetracycline, respectively. Additionally, mutations in the gyrA gene were associated with ciprofloxacin resistance.

The non-toxigenic Corynebacterium diphtheriae strain was found to possess the ErmX gene, which confers resistance to erythromycin and clindamycin.

The study identified various antibiotic resistance genes (ARGs) in river biofilms upstream and downstream of a wastewater treatment plant (WWTP), including qnrA, qnrS, mfsA, ermC, ermX, macB, mefA_10, cat, catB3, aadB, aph(3')-III, AAC(3)-Ib, bacA_1, blaPer-1, blaIMP, blaTEM, blaKPC, blaDHA, cblA, ermC, ermY, ermX, mdtL, cusF, copD, qacA, mecA, dfrF, arnA, sul1, sulA, vat(A), IS6100, ISS1N, Intl1, blaCTX-M, blaIMP, mefA_10, tolC, mdfF, acrA, dfrA27, aac(6')-IIa, vanA, intl3, and TTV. These genes were associated with resistance to various antibiotics such as fluoroquinolones, macrolides, chloramphenicol, aminoglycosides, beta-lactams, polymyxins, sulfonamides, and others. The study also found that the resistome composition varied between upstream and downstream sites, indicating the impact of WWTP effluents on the distribution of ARGs in river biofilms.

The study identifies two new species, Corynebacterium parakroppenstedtii and Corynebacterium pseudokroppenstedtii, and characterizes antibiotic resistance genes including APH(3')-Ia, APH(3'')-Ib, APH(6)-Id, erm(X), sul1, and tet(W) in C. kroppenstedtii-like isolates.

The study reveals widespread macrolide resistance in C. acnes due to the presence of the ermX gene and 23S rDNA point mutations, highlighting the need for improved resistance testing in acne treatment.

The study identified several antibiotic resistance genes (ARGs) in the gut microbiome of Bangladeshi children, including bla CTX-M, mph(A), qnrS1, mdf(A), tet(A), sul2, aadA5, tet(X), erm(X), nimE, dfrA17, bla TEM, and ant(6’)-Ia. These genes were associated with resistance to various antibiotics such as third-generation cephalosporins, azithromycin, fluoroquinolones, tetracyclines, sulfonamides, streptomycin, spectinomycin, macrolides, lincosamides, streptogramin B, nitroimidazoles, trimethoprim, penicillins, and aminoglycosides.

The study identifies the erythromycin resistance gene erm(X) and demonstrates its horizontal transfer among Bifidobacteria via the genomic island BKGI1.

The study identified antibiotic resistance genes ermX, lsaC, tetL, and tetM in Gardnerella strains, with seven strains showing strong resistance to metronidazole.

The study identified a novel 18 kb erm(X)-carrying plasmid in erythromycin-resistant Corynebacterium diphtheriae isolates from Vietnam in the 1990s.

The study identifies 15 antimicrobial resistance genes in Corynebacterium striatum, including genes conferring resistance to aminoglycosides, tetracyclines, chloramphenicol, macrolides, lincosamides, streptogramins, sulfonamides, and cationic antiseptics. These genes are often located in genomic islands and mobile genetic elements, highlighting the role of horizontal gene transfer in the spread of multidrug resistance.

The study identified 40 antibiotic resistance genes (ARGs) in 19 Trueperella pyogenes strains, including genes conferring resistance to aminoglycosides, tetracyclines, phenicols, sulfonamides, and macrolides.

Two multidrug-resistant toxigenic Corynebacterium diphtheriae isolates were analyzed, revealing two novel resistance genomic islands carrying 12 resistance genes, including ermX, cmx, aph(3')-Ib, aph(6)-Id, aadA1, dfrA15, sul1, cmlA, cmlR, and tet(33). Additionally, mutations in rpoB and gyrA were associated with resistance to rifampicin and ciprofloxacin, respectively.

The study identified erm(X), sul(1), and tet(W) genes in Corynebacterium kroppenstedtii isolates, which confer resistance to erythromycin, clindamycin, trimethoprim-sulfamethoxazole, and tetracycline. Additionally, mutations in the gyrA gene were linked to ciprofloxacin resistance.

The study identified a variety of antimicrobial resistance genes in the nasopharynx of COVID-19 patients, including beta-lactamases, macrolide-lincosamide-streptogramin resistance genes, tetracycline resistance genes, and others. These genes were found to be prevalent in both symptomatic and asymptomatic patients, highlighting the importance of monitoring antimicrobial resistance in the context of the pandemic.

The study identifies ermX, tetO, and rpoB as AMR genes in Winkia strains, highlighting differences in resistance profiles between W. neuii and W. anitratus.

The study found that conventionally raised pigs had a significantly higher abundance of antimicrobial resistance genes (ARGs) compared to pasture-raised pigs, particularly for aminoglycosides, beta-lactams, macrolides-lincosamides-streptogramin B, and tetracyclines. Several ARGs, including aph(3')-IIIa, erm(B), erm(X), tet(Q), tet(36), tet(W/N/W), blaOXA-193, and cfxA2, were identified as being more prevalent in the gut microbiome of conventionally raised pigs.

The study identifies rpoB and erm(X) genes in B. breve PRL2020, which are associated with resistance to rifampicin and erythromycin, respectively. However, these resistances are not phenotypically expressed, and the strain remains within EFSA limits for these antibiotics.

The study identifies tetracycline resistance gene tet(W), erythromycin/clindamycin resistance gene ermX, and rifampicin resistance gene rpoB in Bifidobacterium species, highlighting species-specific antibiotic resistance profiles.

The study identifies tetracycline resistance genes (tetM, tetL) and a fluoroquinolone resistance gene (parC) in probiotic strains, highlighting the potential for probiotics to mediate antibiotic resistance.

The study identified several AMR genes in Pasteurella multocida isolates, including ermX (erythromycin resistance), blaROB-1 (beta-lactam resistance), mcr-1 (colistin resistance), sul1 (sulfonamide resistance), dfrA1 (trimethoprim resistance), and tetH (tetracycline resistance).

The study identified several Corynebacterium species, including novel ones, and found that some strains exhibited resistance to clindamycin, penicillin, and ciprofloxacin. The ermX gene was associated with resistance to these antibiotics.

The study identified several AMR genes in Corynebacterium pyruviciproducens strain WYJY-01, including ermX, aph(3')-Ia, aph(3″)-Ib, aph(6)-Id, and cmx, which confer resistance to macrolide, lincosamide, streptogramin, aminoglycoside, and phenicol antibiotics.

The study identified multiple antimicrobial resistance genes in Avibacterium paragallinarum isolates from Guangdong, China, including tet(B), aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, aad-A, sul2, sul3, catP, floR, blaOXA-1, blaCTX-M-14, erm(X), mef(B), and fosA3. These genes were associated with resistance to tetracycline, streptomycin, kanamycin, trimethoprim-sulfamethoxazole, chloramphenicol, ampicillin, erythromycin, and fosfomycin.

The study identified aadA9, tetW, ermX, aadA1, aadA11, strA-strB, and aadB as key AMR genes in T. pyogenes isolates from bovine mastitis in China, highlighting high resistance to streptomycin and tetracycline.

The study identified antimicrobial resistance genes such as erm(X), tet(O), tet(O/23/O), tet(Q), and tet(W) in Bifidobacterium isolates from Cambodian infants, highlighting the presence of resistance mechanisms in the gut microbiota.

The study identified 20 antimicrobial resistance genes in Corynebacterium striatum, with ErmX being the most prevalent. These genes are mainly associated with plasmid sequence regions and class 1 integrons, highlighting the role of mobile genetic elements in the dissemination of resistance.

The study identified eight resistance genes in Trueperella pyogenes isolates from small ruminants in western China, including ant(2")-Ia, ant(3")-Ia, cmlA1, cmx, erm(X), lnu(A), sul1, and tet(W). These genes conferred resistance to various antibiotics such as gentamicin, chloramphenicol, erythromycin, clindamycin, sulfisoxazole, and tetracycline.

The study identified multiple AMR genes in odontogenic abscesses using NGS, including genes conferring resistance to tetracyclines, macrolides, lincosamides, aminoglycosides, chloramphenicol, sulfonamides, penicillins, and others. Notably, Fusobacterium showed resistance to clindamycin.

The study identified multiple antimicrobial resistance (AMR) genes in Trueperella pyogenes, including tet(W/32/O), erm(X), vanG, sul1, and qacEdelta1, which confer resistance to tetracyclines, MLS B, glycopeptides, sulfonamides, and biocides, respectively. These genes were detected in various T. pyogenes isolates from different animal hosts and body sites, highlighting the genetic diversity and potential for AMR dissemination among different hosts.

The study identified bla ROB−1, tet H, and erm X as antibiotic resistance genes in multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Pasteurella multocida isolated from poultry and rabbits.

The study investigated the metabolism of human milk oligosaccharides (HMOs) by bifidobacteria and lactobacilli isolated from human milk and mother-infant fecal samples, along with their antibiotic resistance profiles. Bifidobacterium bifidum showed the highest HMO degradation capability and was the most antibiotic-susceptible species, whereas Bifidobacterium animalis subsp. lactis was resistant to most tested antibiotics.

The study identifies several AMR genes in Corynebacterium macclintockiae, including bla Coryne-A, tet(W), erm(X), and ant(2'')-Ia, which confer resistance to various antibiotics. These genes were experimentally validated through whole-genome sequencing and antimicrobial susceptibility testing.

The study identified multiple AMR genes and mutations in contemporary Corynebacterium diphtheriae isolates from Victoria, Australia, including pbp2m, erm(X), aph(3')-Ia, aph(6)-Id, aph(3'')-Ib, tet(W), tet(33), tet(O), cmx, sul1, dfrA15, and mutations in gyrA and rpoB. These genes and mutations confer resistance to various antimicrobials such as penicillin, erythromycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole, trimethoprim, ciprofloxacin, and rifampicin.

The study identifies ermX-mediated macrolide resistance in genetically homologous Corynebacterium striatum strains isolated from dual anatomical sites in an immunocompromised patient.

The study identified multiple AMR genes, including erm(X), tet(W), and aminoglycoside modifying enzymes, in various Corynebacterium species, highlighting extensive antimicrobial resistance in clinical isolates.