Browse AMR Genes

Explore antimicrobial resistance genes from the literature

ermF

rRNA methylase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ermF

Browse AMR rules for ermF

Overview

Drug Classes: erythromycin|azithromycin, macrolides
Organisms: Neisseria gonorrhoeae
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
C1192Y	-	-	Neisseria gonorrhoeae	erythromycin\|azithromycin	Reslit	Candidate
-	C2611T	-	Neisseria gonorrhoeae	macrolides	Reslit	Candidate

Papers2

1

Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.

PMID 24982323 · 2014

Mutations in ermF lead to resistance to macrolides.

Mutation Information

Protein Change: C1192Y
Organisms: Neisseria gonorrhoeae
Confers Resistance To: erythromycin|azithromycin
Validation Method: reported in cited literature
Source Database: Reslit

2

Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae.

PMID 36142410 · 2022

mutations in ermF lead to macrolide resistance via rRNA methylation

Mutation Information

Nucleotide Change: C2611T
Organisms: Neisseria gonorrhoeae
Confers Resistance To: macrolides
Validation Method: mutational analysis and MIC testing
Source Database: Reslit