Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Acyl carrier protein synthase
Overview
Mycobacterium tuberculosis Whole Genome Sequences From Southern India Suggest Novel Resistance Mechanisms and the Need for Region-Specific Diagnostics.
The study identified novel resistance mechanisms in Mycobacterium tuberculosis strains from Southern India, including mutations in katG, fadE24, fabD, gidB, and rrs that contribute to isoniazid and streptomycin resistance.
Genome-Scale Metabolic Models and Machine Learning Reveal Genetic Determinants of Antibiotic Resistance in Escherichia coli and Unravel the Underlying Metabolic Adaptation Mechanisms.
The study identifies 20 top-ranked genetic determinants associated with antibiotic resistance in E. coli, including genes involved in cell wall metabolism, energy metabolism, and iron metabolism, using a combination of machine learning and genome-scale metabolic models.
Identification of gene targets that potentiate the action of rifampicin on Mycobacterium bovis BCG.
The study identified genes involved in cell wall synthesis, transport, and signaling pathways that contribute to rifampicin resistance in Mycobacterium bovis BCG. Key genes include chp2, pknE, thrE, fabD, iniB, and mce1R, which were found to enhance susceptibility when mutated.
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