Browse AMR Genes

Explore antimicrobial resistance genes from the literature

fabI1

enoyl-ACP reductase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to fabI1

Browse AMR rules for fabI1

Overview

Drug Classes: triclosan
Organisms: Rhodospirillum rubrum
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G98V	-	-	Rhodospirillum rubrum	triclosan	Reslit	Candidate

Papers1

1

Characterization of triclosan-resistant mutants reveals multiple antimicrobial resistance mechanisms in Rhodospirillum rubrum S1H.

PMID 20305019 · 2010

The FabI1(G98V) mutation leads to high-level triclosan resistance.

Mutation Information

Protein Change: G98V
Organisms: Rhodospirillum rubrum
Confers Resistance To: triclosan
Validation Method: sequencing and MIC testing
Source Database: Reslit