Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
ferredoxin-like protein
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| I38V | - | - | Helicobacter pylori | metronidazole | Reslit | Candidate |
Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori.
The study identifies fdxB, frxA, and rdxA as genes involved in metronidazole resistance in Helicobacter pylori through inactivation analysis, complementation, and enzyme assays.
Genome-wide analysis of antibiotic resistance genes and mutations in Helicobacter pylori strains
The study identified several AMR genes and mutations in H. pylori strains associated with resistance to clarithromycin, levofloxacin, and metronidazole. Key findings include mutations in 23S rRNA, gyrA, gyrB, rdxA, frxA, and fdxB genes that confer resistance to these antibiotics.
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