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Explore antimicrobial resistance genes from the literature

fecR

transcriptional regulator

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to fecR

Browse AMR rules for fecR

Overview

Mechanism: compromised
Drug Classes: cefiderocol
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G104S	-	compromised	Escherichia coli	cefiderocol	Reslit	Candidate

Papers1

1

Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics.

PMID 40724005 · 2025

mutated gene associated with reduced cefiderocol susceptibility

Mutation Information

Protein Change: G104S
Organisms: Escherichia coli
Confers Resistance To: cefiderocol
Effect on Function: compromised
Validation Method: structural modeling
Source Database: Reslit