Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
peptidoglycan cross-linking enzyme
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| R199S | - | - | - | oxacillin | Reslit | Candidate |
Rapid PCR-based identification of methicillin-resistant Staphylococcus aureus from screening swabs.
The study describes a rapid PCR-based method for identifying methicillin-resistant Staphylococcus aureus (MRSA) using the mecA and femB genes, which are critical for methicillin resistance.
Antimicrobial resistance and molecular typing of Staphylococcus aureus isolates from raw milk in Hunan Province.
The study identified multiple antimicrobial resistance genes in Staphylococcus aureus isolates from raw milk in Hunan Province, including femB, ermB, aacA-aphD, tetM, flor, and mecA, which conferred resistance to various antibiotics such as penicillin, erythromycin, gentamicin, doxycycline, florfenicol, and others.
Cloning, Purification, and Biophysical Characterization of FemB Protein from Methicillin-Resistant Staphylococcus aureus and Inhibitors Screening
The study identified the FemB protein from Methicillin-Resistant Staphylococcus aureus (MRSA) as a key player in methicillin resistance through its role in peptidoglycan cross-linking. The protein was cloned, purified, and characterized, and a novel inhibitor was identified that shows potent activity against MRSA.
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