Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
F420 recycling enzyme
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| Q88E | - | - | Mycobacterium tuberculosis | pa 824 | Reslit | Candidate |
| K296E | - | - | Mycobacterium tuberculosis | delamanid|pretomanid | Reslit | Candidate |
| G34D | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| L70R | - | - | - | delamanid | Reslit | Candidate |
| M93R | - | - | - | delamanid | Reslit | Candidate |
| W284S | - | - | - | delamanid | Reslit | Candidate |
| G304V | - | - | - | delamanid | Reslit | Candidate |
| L321P | - | - | - | delamanid | Reslit | Candidate |
| S960P | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| R409Q | - | - | - | delamanid|clofazimine | Reslit | Candidate |
| 49fs | - | - | - | delamanid|pretomanid | Reslit | Candidate |
| F250C | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| R269C | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| G273R | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| R280C | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate | |
| V310D | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| F322S | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
| V1Var | - | single resistance variant | Mycobacterium tuberculosis | delamanid | Card Database | Candidate |
| - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
This study identifies numerous mutations in genes associated with resistance to bedaquiline, clofazimine, linezolid, delamanid, and pretomanid in Mycobacterium tuberculosis, highlighting the genetic basis of resistance to these drugs.
Genomic analysis of Mycobacterium tuberculosis variant bovis strains isolated from bovine in the state of Mato Grosso, Brazil.
The study identified multiple AMR genes and mutations in Mycobacterium tuberculosis variant bovis strains from Mato Grosso, Brazil, including resistance to pyrazinamide, isoniazid, rifampicin, streptomycin, ethambutol, ethionamide, fluoroquinolones, kanamycin, capreomycin, paraminosalicylic acid, cycloserine, bedaquiline, linezolid, and delamanid.
Investigation of delamanid, bedaquiline, and linezolid resistance rates and related gene mutations in multidrug-resistant Mycobacterium tuberculosis in regional tuberculosis reference laboratories of Iran.
This study identified multiple mutations in the fgd1, fbiA, fbiC, rplC, and rrl genes associated with delamanid and linezolid resistance in multidrug-resistant Mycobacterium tuberculosis isolates in Iran.
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