Browse AMR Genes

Explore antimicrobial resistance genes from the literature

fis

global regulatory protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to fis

Browse AMR rules for fis

Overview

Drug Classes: aztreonam|clavulanic acid
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E674D	-	-	Escherichia coli	aztreonam\|clavulanic acid	Reslit	Candidate

Papers1

1

The impact of aztreonam-clavulanic acid exposure on gene expression and mutant selection using a multidrug-resistant E. coli.

PMID 39932309 · 2025

encoding the global regulatory protein Fis

Mutation Information

Protein Change: E674D
Organisms: Escherichia coli
Confers Resistance To: aztreonam|clavulanic acid
Validation Method: whole-genome sequencing and MIC test
Source Database: Reslit