Browse AMR Genes

Explore antimicrobial resistance genes from the literature

folE

GTP cyclohydrolase 1

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to folE

Browse AMR rules for folE

Overview

Drug Classes: trimethoprim
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
S206P	-	-	-	trimethoprim	Reslit	Candidate

Papers1

1

Multiple Novel Traits without Immediate Benefits Originate in Bacteria Evolving on Single Antibiotics.

PMID 34865131 · 2022

A SNP in folE confers resistance to trimethoprim.

Mutation Information

Protein Change: S206P
Confers Resistance To: trimethoprim
Validation Method: genomic sequencing; mutant analysis
Source Database: Reslit