Browse AMR Genes

Explore antimicrobial resistance genes from the literature

fupA/B

iron transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to fupA/B

Browse AMR rules for fupA/B

Overview

Mechanism: modest increase in resistance
Drug Classes: doxycycline|ciprofloxacin
Organisms: Francisella tularensis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R343I	-	modest increase in resistance	Francisella tularensis	doxycycline\|ciprofloxacin	Reslit	Candidate

Papers1

1

Mutational Switch-Backs Can Accelerate Evolution of Francisella to a Combination of Ciprofloxacin and Doxycycline.

PMID 35615518 · 2022

Mutation Information

fupA/B: p.R343I

Protein Change: R343I
Organisms: Francisella tularensis
Confers Resistance To: doxycycline|ciprofloxacin
Effect on Function: modest increase in resistance
Validation Method: mutant construction and MIC testing
Source Database: Reslit