Browse AMR Genes

Explore antimicrobial resistance genes from the literature

gacS

histidine kinase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to gacS

Browse AMR rules for gacS

Overview

Drug Classes: tobramycin
Organisms: Pseudomonas aeruginosa
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
L303H	-	-	Pseudomonas aeruginosa	tobramycin	Reslit	Candidate

Papers1

1

The Effects of Sub-inhibitory Antibiotic Concentrations on Pseudomonas aeruginosa: Reduced Susceptibility Due to Mutations.

PMID 34987489 · 2021

Mutation Information

Protein Change: L303H
Organisms: Pseudomonas aeruginosa
Confers Resistance To: tobramycin
Validation Method: whole-genome sequencing
Source Database: Reslit