Browse AMR Genes

Explore antimicrobial resistance genes from the literature

gadC

glutamate/gamma-aminobutyrate transporter

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to gadC

Browse AMR rules for gadC

Overview

Drug Classes: amikacin
Organisms: Escherichia coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G212D	G634A	-	Escherichia coli	amikacin	Reslit	Candidate

Papers1

1

Evolution of Bacterial Tolerance Under Antibiotic Treatment and Its Implications on the Development of Resistance.

PMID 33717007 · 2021

mutated in Clone 6-1

Mutation Information

gadC: p.G212D / c.G634A

Protein Change: G212D
Nucleotide Change: G634A
Organisms: Escherichia coli
Confers Resistance To: amikacin
Validation Method: laboratory evolution experiment
Source Database: Reslit