Browse AMR Genes

Explore antimicrobial resistance genes from the literature

gidA

GTP-binding protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to gidA

Browse AMR rules for gidA

Overview

Drug Classes: imipenem
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A539V	-	-	Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa	imipenem	Reslit	Candidate

Papers1

1

Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria.

PMID 31744905 · 2019

Mutation in gidA showed inconsistent resistance phenotype.

Mutation Information

Protein Change: A539V
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa
Confers Resistance To: imipenem
Validation Method: knock-in approach
Source Database: Reslit