Browse AMR Genes

Explore antimicrobial resistance genes from the literature

gpsI

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to gpsI

Browse AMR rules for gpsI

Overview

Mechanism: single resistance variant
Drug Classes: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
C160G	-	single resistance variant	Mycobacterium tuberculosis	pyrazinamide	Card Database	Candidate

Papers1

1

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

PMID 30337678 · 2018

Mycobacterium tuberculosis gpsI with mutations conferring resistance to pyrazinamide; CARD accession: CARD:3004977

Mutation Information

Protein Change: C160G
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Effect on Function: single resistance variant
Source Database: Card Database