Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
two-component response regulator
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| E15K | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| S79F | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| N197S | - | increased vancomycin resistance | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| D148Q | - | - | - | teicoplaninvancomycin | Reslit | Candidate |
| H481Y | - | - | - | teicoplanin | Reslit | Candidate |
| H481N | - | - | - | teicoplanin | Reslit | Candidate |
| D147E | - | - | - | teicoplanin | Reslit | Candidate |
| E224D | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| V6L | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| E120D | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
| V216* | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus.
The study identifies 17 genes associated with glycopeptide resistance in Staphylococcus aureus, including 8 novel genes. Overexpression of these genes, particularly graF and msrA2, significantly increases resistance to vancomycin, teicoplanin, and oxacillin.
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