Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Aminoglycoside ribose transferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| grdA | ResFinder Database | 1 | SISOMICIN, GENTAMICIN | Salmonella sp. | - | 2020 | QJX10702 | - |
| grd A | Reslit | 1 | aminoglycosides | Salmonella enterica subsp. enterica serovar Heidelberg | Ontario, Canada | 2022 | PRJNA845137 | - |
| GrdA | Reference Gene CatalogReslit | 3 | gentamicin, plazomicin +2 | Salmonella enterica +2 | United States, Europe | 2024, 2025 | PRJNA993710 | EAO1346689.1 |
Identification of a Novel Plasmid-Borne Gentamicin Resistance Gene in Nontyphoidal Salmonella Isolated from Retail Turkey.
Combining analytical epidemiology and genomic surveillance to identify risk factors associated with the spread of antimicrobial resistance in Salmonella enterica subsp. enterica serovar Heidelberg.
The study identified multiple AMR genes in Salmonella enterica subsp. enterica serovar Heidelberg, including bla CMY-2, bla TEM-1A, bla TEM-1B, bla TEM-214, mcr -9, and others, highlighting the prevalence of resistance to beta-lactams, aminoglycosides, and other antimicrobial agents.
Comparison of genotypic and phenotypic antimicrobial resistance profiles of Salmonella enterica isolates from poultry diagnostic specimens.
The study identified 31 AMR genes in 97 Salmonella enterica isolates from poultry, including aac(3)-IId, aac(3)-IVa, aac(3)-VIa, aac(6′)-Ib4, ant(2′′)-Ia, grdA, aph(3′)-Ia, aph(3′)-IIa, aadA1, aadA2, aadA7, aadA13, aph(3′)-Ib, aph(6)-Ic, aph(6)-Id, aph(4)-Ia, blaCMY-2, blaCTX-M-1, blaHER-3, blaTEM-1, floR, tetA, tetB, tetC, dfrA12, sul1, sul2, fosA7, qnrB19, ble, and mcr-9.
The newly identified grdA gene confers high-level plazomicin resistance in Salmonella enterica serovars.
The study identifies the grdA gene as a novel determinant of high-level plazomicin resistance in Salmonella enterica serovars, demonstrating that heterologous expression of grdA in E. coli Delta tolC leads to plazomicin resistance with MIC > 256 mu g/mL.
The newly identified grdA gene confers high-level plazomicin resistance in Salmonella enterica serovars.
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