hpf

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Ribosome hibernation promotion factor

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Validation StatusCandidate

Overview

Validation Method: Genomic analysis and mutant screening
Drug Classes: gentamicin
Organisms: Listeria monocytogenes
Papers: 1
Databases: Reslit

Papers1

Chemical mutagenesis of Listeria monocytogenes for increased tolerance to benzalkonium chloride shows independent genetic underpinnings and off-target antibiotic resistance.

PMID 39028728 · 2024

The study identifies specific mutations in genes such as dagK, lmo2768, lmo0186, and uvrB that contribute to increased benzalkonium chloride tolerance in Listeria monocytogenes mutants, along with off-target antibiotic resistance.

Gene Information

Gene Name: hpf
Allele: hpf
Encodes: Ribosome hibernation promotion factor
Source Database: Reslit
Confers Resistance To: gentamicin
Organisms Tested In: • Listeria monocytogenes
Validation Method: Genomic analysis and mutant screening
Sequence Accession: SRR17006605|SRR17067427

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hpf

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hpf

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