Browse AMR Genes

Explore antimicrobial resistance genes from the literature

hpt

Hypoxanthine-guanine phosphoribosyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to hpt

Browse AMR rules for hpt

Overview

Drug Classes: oxacillin
Organisms: Staphylococcus aureus
Papers: 1
Mutations: 5

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A167D	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
T106I	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
P175S	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
R139H	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
T103A	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate

Papers1

1

Genetic Determinants of High-Level Oxacillin Resistance in Methicillin-Resistant Staphylococcus aureus.

PMID 29555636 · 2018

Mutation Information

hpt: p.A167D hpt: p.T106I hpt: p.P175S hpt: p.R139H hpt: p.T103A

Protein Change: A167D, T106I, P175S, R139H, T103A
Organisms: Staphylococcus aureus
Confers Resistance To: oxacillin
Validation Method: whole-genome sequencing
Source Database: Reslit