Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
adenine methyltransferase
Overview
The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility.
The study identifies HsdM as a DNA methyltransferase that decreases intrinsic isoniazid susceptibility in Mycobacterium bovis BCG and Mycobacterium tuberculosis by modifying gene expression through DNA methylation.
DNA Methyltransferase HsdM Induce Drug Resistance on Mycobacterium tuberculosis via Multiple Effects.
The study shows that the DNA methyltransferase HsdM affects drug resistance in Mycobacterium tuberculosis by modulating gene expression of redox, drug targets, and transporters, and increasing mutation rates.
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