ihfA

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DNA-binding protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to ihfA

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Validation StatusCandidate

Overview

Mechanism: loss of function
Validation Method: genomic sequencing and complementation assay
Drug Classes: polymyxin b
Organisms: Vibrio cholerae O1 El Tor A1552
Geographic Location: Global
Papers: 1
Databases: Reslit

Papers1

Mechanisms of Polymyxin B Resistance in Vibrio cholerae Variants Through Membrane Vesicle Production and Genetic Mutations

PMID 36090081 · 2023

Mutations in vacJ, mlaF, dacB, and ihfA contribute to polymyxin B resistance in Vibrio cholerae variants through hypervesiculation and membrane remodeling.

Gene Information

Gene Name: ihfA
Allele: ihfA
Encodes: DNA-binding protein
Source Database: Reslit
Mechanism: loss of function
Confers Resistance To: polymyxin b
Organisms Tested In: • Vibrio cholerae O1 El Tor A1552
Geographic Location: Global
Validation Method: genomic sequencing and complementation assay
Sequence Accession: NCBI Accession Number 1|NCBI Accession Number 2

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ihfA

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ihfA

Gene Information