Browse AMR Genes

Explore antimicrobial resistance genes from the literature

iscS

iron-sulfur protein assembly protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to iscS

Browse AMR rules for iscS

Overview

Drug Classes: cefiderocol
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
N302K	-	-	Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii	cefiderocol	Reslit	Candidate

Papers1

1

In vitro resistance development gives insights into molecular resistance mechanisms against cefiderocol.

PMID 39080477 · 2024

Mutation Information

Protein Change: N302K
Organisms: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii
Confers Resistance To: cefiderocol
Validation Method: whole-genome sequencing
Source Database: Reslit