Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| V146W | - | - | Escherichia coli | gentamicin | Reslit | Candidate |
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks.
Metabolic mutations in E. coli lead to pathway-specific bottlenecks that reduce antibiotic susceptibility, particularly affecting purine nucleotide biosynthesis for carbenicillin and respiratory chain pathways for gentamicin.
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