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Browse GeneskatA

katA

catalase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to katA

Browse AMR rules for katA

Validation StatusCandidate

Overview

Validation Method: overexpression in ΔarcR mutant restored bacterial resistance to oxidative stress and antibiotics
Drug Classes: fluoroquinolones
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

1

ArcR contributes to tolerance to fluoroquinolone antibiotics by regulating katA in Staphylococcus aureus.

PMID 36910210 · 2023

ArcR regulates katA expression, which is crucial for bacterial tolerance to oxidative stress and fluoroquinolone antibiotics.

Gene Information

Gene Name: katA
Allele: katA
Encodes: catalase
Source Database: Reslit
Confers Resistance To: fluoroquinolones
Organisms Tested In: • Staphylococcus aureus
Validation Method: overexpression in ΔarcR mutant restored bacterial resistance to oxidative stress and antibiotics

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research