kdeA

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multidrug efflux MFS transporter KdeA

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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Validation StatusConfirmed2+ DBs

Overview

Validation Method: qRT-PCR
Drug Classes: EFFLUX, aztreonam, ceftazidime, imipenem
Organisms: Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae
Geographic Location: India
Papers: 2
Databases: Reference Gene CatalogReslit

Papers2

Gene cloning and characterization of KdeA, a multidrug efflux pump from Klebsiella pneumoniae.

PMID 17917272 · 2007

Gene Information

Gene Name: kdeA
Allele: KdeA
Encodes: multidrug efflux MFS transporter KdeA
Source Database: Reference Gene Catalog
Confers Resistance To: EFFLUX
Organisms Tested In: • Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Sequence Accession: CP000647.1
Protein Accession: ABR76310.1

Alliance of Efflux Pumps with β-Lactamases in Multidrug-Resistant Klebsiella pneumoniae Isolates.

PMID 31613200 · 2019

The study identified bla CTX-M-15 and bla NDM as prevalent β-lactamase genes in multidrug-resistant K. pneumoniae isolates. Additionally, several efflux pump genes including acrB, oqxA, kexD, kdeA, and kpnF were found to contribute to β-lactam resistance.

Gene Information

Gene Name: kdeA
Allele: KdeA
Encodes: MATE efflux pump
Source Database: Reslit
Confers Resistance To: aztreonamceftazidimeimipenem
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: India
Validation Method: qRT-PCR

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kdeA

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kdeA

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