Browse AMR Genes

Explore antimicrobial resistance genes from the literature

ktrA

potassium transporter subunit A

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ktrA

Browse AMR rules for ktrA

Overview

Drug Classes: aminoglycosides
Organisms: Staphylococcus aureus
Papers: 1
Mutations: 3

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
E76G	A228G	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
H47Y	C141T	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
A178V	C535T	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate

Papers1

1

Evolution of polyamine resistance in Staphylococcus aureus through modulation of potassium transport.

PMID 40824070 · 2025

Mutation Information

ktrA: p.E76G / c.A228G ktrA: p.H47Y / c.C141T ktrA: p.A178V / c.C535T

Protein Change: E76G, H47Y, A178V
Nucleotide Change: A228G, C141T, C535T
Organisms: Staphylococcus aureus
Confers Resistance To: aminoglycosides
Validation Method: mutagenesis and MIC testing
Source Database: Reslit