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Explore antimicrobial resistance genes from the literature

ktrD

potassium transporter subunit D

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ktrD

Browse AMR rules for ktrD

Overview

Drug Classes: aminoglycosides
Organisms: Staphylococcus aureus
Papers: 1
Mutations: 5

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
Q450K	C1350A	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
S135L	C406T	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
T277N	C832A	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
M391I	G1175T	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate
G94V	G283T	-	Staphylococcus aureus	aminoglycosides	Reslit	Candidate

Papers1

1

Evolution of polyamine resistance in Staphylococcus aureus through modulation of potassium transport.

PMID 40824070 · 2025

Mutation Information

ktrD: p.Q450K / c.C1350A ktrD: p.S135L / c.C406T ktrD: p.T277N / c.C832A ktrD: p.M391I / c.G1175T ktrD: p.G94V / c.G283T

Protein Change: Q450K, S135L, T277N, M391I, G94V
Nucleotide Change: C1350A, C406T, C832A, G1175T, G283T
Organisms: Staphylococcus aureus
Confers Resistance To: aminoglycosides
Validation Method: mutagenesis and MIC testing
Source Database: Reslit