ktrbd

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Ktr channel proteins

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to ktrbd

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Validation StatusCandidate

Overview

Mechanism: maintains intracellular K+ and Na+ pools
Validation Method: ICP-MS measurement of intracellular K+ and Na+
Drug Classes: ampicillin, penicillin, gentamicin, amikacin
Organisms: Staphylococcus aureus
Papers: 1
Databases: Reslit

Papers1

Temporal control of Staphylococcus aureus intracellular pH by sodium and potassium.

PMID 39567841 · 2024

The study identifies the Ktr system in Staphylococcus aureus as crucial for intracellular pH regulation and conferring resistance to ampicillin, penicillin, gentamicin, and amikacin. Disruption of the Ktr system leads to decreased resistance to these antibiotics.

Gene Information

Gene Name: ktrbd
Allele: ktrBD
Encodes: Ktr channel proteins
Source Database: Reslit
Mechanism: maintains intracellular K+ and Na+ pools
Confers Resistance To: ampicillinpenicillingentamicinamikacin
Organisms Tested In: • Staphylococcus aureus
Validation Method: ICP-MS measurement of intracellular K+ and Na+

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ktrbd

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ktrbd

Gene Information