Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
transcriptional regulator
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| 93del | - | - | Pseudomonas aeruginosa | ceftazidime avibactam|imipenem relebactam|meropenem vaborbactam | Reslit | Candidate |
| V208G | - | loss of function | Pseudomonas aeruginosa | beta lactams | Reslit | Candidate |
| A140D | - | - | - | ciprofloxacin|ceftazidime|meropenem | Reslit | Candidate |
| A206V | - | - | - | ciprofloxacin|ceftazidime|meropenem | Reslit | Candidate |
| Q45X | - | Pseudomonas aeruginosa | ceftazidime avibactam|imipenem relebactam|meropenem vaborbactam | Reslit | Candidate | |
| - | - | Pseudomonas aeruginosa | polymyxins | Reslit | Candidate | |
| W187X | - | Pseudomonas aeruginosa | ceftazidime avibactam|imipenem relebactam|meropenem vaborbactam | Reslit | Candidate |
Allelic polymorphism shapes community function in evolving Pseudomonas aeruginosa populations.
The study identifies a lasR V208G mutation associated with increased beta-lactam resistance in Pseudomonas aeruginosa populations evolved in synthetic cystic fibrosis sputum medium.
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