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ldtMt2

L,D-transpeptidase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to ldtMt2

Browse AMR rules for ldtMt2

Overview

Drug Classes: carbapenems
Organisms: Mycobacterium tuberculosis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R209E	-	-	Mycobacterium tuberculosis	carbapenems	Reslit	Candidate

Papers1

1

Allosteric cooperation in β-lactam binding to a non-classical transpeptidase.

PMID 35475970 · 2022

Mutation Information

ldtMt2: p.R209E

Protein Change: R209E
Organisms: Mycobacterium tuberculosis
Confers Resistance To: carbapenems
Validation Method: mutational analysis and MD simulations
Source Database: Reslit