Browse AMR Genes

Explore antimicrobial resistance genes from the literature

liaX

cell envelope stress response protein

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to liaX

Browse AMR rules for liaX

Overview

Drug Classes: daptomycin
Organisms: Enterococcus faecium
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
V123A	-	-	Enterococcus faecium	daptomycin	Reslit	Candidate

Papers1

1

LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.

PMID 38289081 · 2024

Amino acid substitution in LiaX correlates with daptomycin resistance.

Mutation Information

Protein Change: V123A
Organisms: Enterococcus faecium
Confers Resistance To: daptomycin
Validation Method: association with daptomycin MICs and LiaX ELISA
Source Database: Reslit