linj.36.2510

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sterol 24-c-methyltransferase (SMT)

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UniProt

Protein entries specific to linj.36.2510

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Validation StatusCandidate

Overview

Validation Method: transfection experiments demonstrating PMM resistance
Drug Classes: amphotericin b
Organisms: Leishmania donovani
Papers: 1
Databases: Reslit

Papers1

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.

PMID 29689531 · 2018

The study identifies LinJ.36.2510 (SMT) as associated with AmB resistance and the tandem D-LDH-BCAT amplification as linked to PMM resistance in Leishmania donovani.

Gene Information

Gene Name: linj.36.2510
Allele: LinJ.36.2510
Encodes: sterol 24-c-methyltransferase (SMT)
Source Database: Reslit
Confers Resistance To: amphotericin b
Organisms Tested In: • Leishmania donovani
Validation Method: transfection experiments demonstrating PMM resistance
Sequence Accession: PRJEB20187

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linj.36.2510

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linj.36.2510

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