lmo0762

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ribosome-splitting factor

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Validation StatusCandidate

Overview

Mechanism: mediates antibiotic resistance through ribosome splitting and recycling
Validation Method: MIC assay, qRT-PCR, Western blot
Drug Classes: lincomycin, erythromycin
Organisms: Listeria monocytogenes
Papers: 1
Databases: Reslit

Papers1

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance.

PMID 30545912 · 2018

The study identifies hflXr (also called lmo0762) as an antibiotic resistance gene in Listeria monocytogenes, which confers protection against lincomycin and erythromycin by mediating ribosome splitting and recycling.

Gene Information

Gene Name: lmo0762
Allele: lmo0762
Encodes: ribosome-splitting factor
Source Database: Reslit
Mechanism: mediates antibiotic resistance through ribosome splitting and recycling
Confers Resistance To: lincomycinerythromycin
Organisms Tested In: • Listeria monocytogenes
Validation Method: MIC assay, qRT-PCR, Western blot
Sequence Accession: PRJEB25942

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lmo0762

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lmo0762

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