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Explore antimicrobial resistance genes from the literature

lnuC

ribosomal RNA methyltransferase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to lnuC

Browse AMR rules for lnuC

Overview

Drug Classes: linezolid
Organisms: Mycobacterium abscessus, Mycobacterium smegmatis
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	A2611G	-	Mycobacterium abscessus, Mycobacterium smegmatis	linezolid	Reslit	Candidate

Papers1

1

Ribosomal protection as a linezolid resistance mechanism in Mycobacterium abscessus.

PMID 41279841 · 2025

mutation identified in linezolid-resistant clinical isolates

Mutation Information

Nucleotide Change: A2611G
Organisms: Mycobacterium abscessus, Mycobacterium smegmatis
Confers Resistance To: linezolid
Validation Method: sequencing of 23S rRNA gene
Source Database: Reslit