Browse AMR Genes

Explore antimicrobial resistance genes from the literature

lpxR

lipid A deacylase outer membrane porin

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to lpxR

Browse AMR rules for lpxR

Overview

Drug Classes: ceftiofur
Organisms: Salmonella enterica
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R303L	-	-	Salmonella enterica	ceftiofur	Reslit	Candidate

Papers1

1

Genomic and Proteomic Analyses of Salmonella enterica Serovar Enteritidis Identifying Mechanisms of Induced de novo Tolerance to Ceftiofur.

PMID 30250458 · 2018

SNP observed in the LpxR gene in the ceftiofur tolerant lineages

Mutation Information

Protein Change: R303L
Organisms: Salmonella enterica
Confers Resistance To: ceftiofur
Validation Method: whole genome sequencing and comparative genomics
Source Database: Reslit