mara47 yp

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transcriptional activator

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to mara47 yp

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Validation StatusCandidate

Overview

Mechanism: overexpression of AcrAB multidrug efflux pump
Validation Method: cloning in E. coli + drug susceptibility testing
Drug Classes: tetracycline, doxycycline, rifampicin, phenicols, norfloxacin, nalidixic acid
Organisms: Escherichia coli, Yersinia pestis
Papers: 1
Databases: Reslit

Papers1

MarA-like regulator of multidrug resistance in Yersinia pestis.

PMID 16940090 · 2006

The study identifies marA47 Yp as a MarA-like regulator in Yersinia pestis that confers multidrug resistance by overexpressing the AcrAB efflux pump, demonstrating resistance to various antibiotics and organic solvents.

Gene Information

Gene Name: mara47 yp
Allele: marA47 Yp
Encodes: transcriptional activator
Source Database: Reslit
Mechanism: overexpression of AcrAB multidrug efflux pump
Confers Resistance To: tetracyclinedoxycyclinerifampicinphenicolsnorfloxacinnalidixic acid
Organisms Tested In: • Escherichia coli
• Yersinia pestis
Validation Method: cloning in E. coli + drug susceptibility testing

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mara47 yp

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mara47 yp

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