Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
metallo-beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| MBL | Reslit | 1 | imipenem, meropenem | Pseudomonas aeruginosa +1 | Europe | 2022 | - | - |
| mbL | Reslit | 1 | carbapenems | Pseudomonas aeruginosa | Southern Thailand | 2025 | - | - |
Gram-Negative Rods on Inanimate Surfaces of Selected Hospital Facilities and Their Nosocomial Significance.
The study identified various AMR genes and mutations in gram-negative rods isolated from inanimate surfaces of hospital facilities, highlighting the presence of resistance mechanisms such as beta-lactamases, ESBLs, Qnr, OXA-48, and MBL.
Antimicrobial Resistance and Mortality in Carbapenem-Resistant Pseudomonas aeruginosa Infections in Southern Thailand.
The study identified the upregulation of the MexAB-OprM efflux pump, downregulation of the OprD porin, production of metallo-beta-lactamases (MBLs), and overexpression of bla AmpC as the primary resistance mechanisms in carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates. Colistin and amikacin remained effective against these isolates.
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