mdfa2

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efflux pump

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to mdfa2

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Validation StatusCandidate

Overview

Validation Method: cloning in E. coli + MIC testing
Drug Classes: florfenicol, phenicols
Organisms: Klebsiella pneumoniae R46, Escherichia coli DH5 alpha
Geographic Location: South China
Papers: 1
Databases: Reslit

Papers1

Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit.

PMID 31531339 · 2019

The study identified a novel chromosome-encoded florfenicol resistance gene, mdfA2, and the floR gene in the multidrug-resistant Klebsiella pneumoniae strain R46. Both genes conferred resistance to florfenicol and chloramphenicol.

Gene Information

Gene Name: mdfa2
Allele: mdfA2
Encodes: efflux pump
Source Database: Reslit
Confers Resistance To: florfenicolphenicols
Organisms Tested In: • Klebsiella pneumoniae R46
• Escherichia coli DH5 alpha
Geographic Location: South China
Validation Method: cloning in E. coli + MIC testing
Sequence Accession: CP035777|CP035774|CP035775|CP035776

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mdfa2

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mdfa2

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