Browse AMR Genes

Explore antimicrobial resistance genes from the literature

mdr

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to mdr

Browse AMR rules for mdr

Overview

Drug Classes: chloroquine|amodiaquine, lumefantrine|mefloquine, chloroquine|mefloquine
Organisms: Plasmodium falciparum
Papers: 1
Mutations: 8

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
N86Y	-	-	Plasmodium falciparum	chloroquine\|amodiaquine	ResFinder Database	Candidate
Y86N	-	-	Plasmodium falciparum	lumefantrine\|mefloquine	ResFinder Database	Candidate
Y184F	-	-	Plasmodium falciparum	lumefantrine\|mefloquine	ResFinder Database	Candidate
F184Y	-	-	Plasmodium falciparum	chloroquine\|amodiaquine	ResFinder Database	Candidate
S1034C	-	-	Plasmodium falciparum	chloroquine\|mefloquine	ResFinder Database	Candidate
N1042D	-	-	Plasmodium falciparum	chloroquine\|mefloquine	ResFinder Database	Candidate
D1246Y	-	-	Plasmodium falciparum	chloroquine\|amodiaquine	ResFinder Database	Candidate
Y1246D	-	-	Plasmodium falciparum	lumefantrine\|mefloquine	ResFinder Database	Candidate

Papers1

1

Mutation Information

mdr: p.N86Y mdr: p.Y86N mdr: p.Y184F mdr: p.F184Y mdr: p.S1034C mdr: p.N1042D mdr: p.D1246Y mdr: p.Y1246D

Protein Change: N86Y, Y86N, Y184F, F184Y, S1034C, N1042D, D1246Y, Y1246D
Organisms: Plasmodium falciparum
Confers Resistance To: chloroquine|amodiaquinelumefantrine|mefloquinechloroquine|mefloquine
Source Database: ResFinder Database