mdtO

major facilitator superfamily (MFS) antibiotic efflux pump

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: whole-genome sequencing and in silico analysis
Drug Classes: tetracycline, trimethoprim, streptomycin, sulfamethoxazole
Organisms: Escherichia coli str. K-12 substr. W3110, Escherichia coli
Geographic Location: Brazil
Papers: 1
Databases: Card DatabaseReslit

Papers1

Gene Information

Gene Name: mdtO
Allele: mdtO
Encodes: major facilitator superfamily (MFS) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Organisms Tested In: • Escherichia coli str. K-12 substr. W3110
Sequence Accession: AP009048.1
Protein Accession: BAE78083.1
Notes: ARO:3003549

Genomic Dissection of an Enteroaggregative Escherichia coli Strain Isolated from Bacteremia Reveals Insights into Its Hybrid Pathogenic Potential.

PMID 39273188 · 2024

The study identifies multiple efflux pump-encoding genes in the E. coli strain EC092, which contribute to its resistance against several antibiotics including tetracycline, trimethoprim, streptomycin, and sulfamethoxazole.

Gene Information

Gene Name: mdtO
Allele: mdtO
Encodes: efflux pump component
Source Database: Reslit
Confers Resistance To: tetracyclinetrimethoprimstreptomycinsulfamethoxazole
Organisms Tested In: • Escherichia coli
Geographic Location: Brazil
Validation Method: whole-genome sequencing and in silico analysis
Sequence Accession: GCA_024199065.1|PRJNA855471

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mdtO

major facilitator superfamily (MFS) antibiotic efflux pump

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to mdtO

AMR Rules

Browse AMR rules for mdtO

Validation StatusConfirmed2+ DBs

Overview

Mechanism: antibiotic efflux
Validation Method: whole-genome sequencing and in silico analysis
Drug Classes: tetracycline, trimethoprim, streptomycin, sulfamethoxazole
Organisms: Escherichia coli str. K-12 substr. W3110, Escherichia coli
Geographic Location: Brazil
Papers: 1
Databases: Card DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: mdtO
Allele: mdtO
Encodes: major facilitator superfamily (MFS) antibiotic efflux pump
Source Database: Card Database
Mechanism: antibiotic efflux
Organisms Tested In: • Escherichia coli str. K-12 substr. W3110
Sequence Accession: AP009048.1
Protein Accession: BAE78083.1
Notes: ARO:3003549

Genomic Dissection of an Enteroaggregative Escherichia coli Strain Isolated from Bacteremia Reveals Insights into Its Hybrid Pathogenic Potential.

PMID 39273188 · 2024

Gene Information

Gene Name: mdtO
Allele: mdtO
Encodes: efflux pump component
Source Database: Reslit
Confers Resistance To: tetracyclinetrimethoprimstreptomycinsulfamethoxazole
Organisms Tested In: • Escherichia coli
Geographic Location: Brazil
Validation Method: whole-genome sequencing and in silico analysis
Sequence Accession: GCA_024199065.1|PRJNA855471

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mdtO

Gene Information

Gene Information

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mdtO

Gene Information

Gene Information